Mapping the Statistics of the Human B cell system
A systems-level view of B cells
Read moreIvana Cvijovic and I generated a systems-level perspective of the human B cell system. Our study provides crucial insights into long-term antibody memory in Humans and informs non-invasive immune monitoring.
Key findings:
- Long-term antibody memory emerges uniformly throughout the immune response
- Proliferative antibody-secreting cells uniquely circulate among multiple tissues
- Interpreting a sample of the immune system in the peripheral blood has strong caveats